Technical Data
A2296-74A
Ansatrienin B (Antibiotic T 23II, Mycotrienin II, T 23II)
1mg
Biochemicals Storage: -20CShipping: Blue Ice
Also know as Mycotrienin II and Antibiotic T 23II, Ansatrienin B isolated from a Streptomyces sp. is closely related to the Cytotrienins. It displays potent anticancer activity against cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents.

Purity: >95% by HPLC

Solubility: Soluble in ethanol, methanol, DMF or DMSO

Related to: Ansatrienin A

CAS Number:
82189-04-6

Molecular Formula:
C36H50N2O8

Molecular Weight:
638.8
Source: Streptomyces sp

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. Feuerbach D. et al.
J. Biol. Chem. 1995, 270, 25949. 2. Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluoro-uracil by mycotrienins and mycotrienols. Kuwano M. et al. Gann. 1983, 74, 759. 3. Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II. Sugita M. et al. J. Antibiot. 1982, 35, 1467.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.