Technical Data
A2296-74A
Ansatrienin B (Antibiotic T 23II, Mycotrienin II, T 23II)
1mg
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Technical Data |
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A2296-74A |
Ansatrienin B (Antibiotic T 23II, Mycotrienin II, T 23II) |
1mg |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Also know as Mycotrienin II and Antibiotic T 23II, Ansatrienin B isolated from a Streptomyces sp. is closely related to the Cytotrienins. It displays potent anticancer activity against cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO Related to: Ansatrienin A CAS Number: 82189-04-6 Molecular Formula: C36H50N2O8 Molecular Weight: 638.8 |
Source: Streptomyces sp Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. Feuerbach D. et al. J. Biol. Chem. 1995, 270, 25949. 2. Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluoro-uracil by mycotrienins and mycotrienols. Kuwano M. et al. Gann. 1983, 74, 759. 3. Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II. Sugita M. et al. J. Antibiot. 1982, 35, 1467.
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