Technical Data
A2296-82C-PE
AGR2, ID (Anterior Gradient Protein 2 Homolog, Secreted Cement Gland Protein XAG-2 Homolog, AG-2, hAG-2, HPC8, AG2, Anterior Gradient 2, UNQ515/PRO1030) (PE)
Description:
Anterior gradient 2 (AGR2) is known as a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. AGR2 has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells (CTCs). Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells, but conditions leading to increased expression of AGR2 are not well understood.

Applications:
Suitable for use in FLISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
FLISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C before opening. DO NOT FREEZE! Stable at 4C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

Note: Applications are based on unconjugated antibody.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul4C Do Not FreezeBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the Center region of human AGR2 (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (R-PE).
Specificity:
Recognizes human AGR2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Zweitzig,D.R., Mol. Cell. Biochem. 306(1-2), 255-260 (2007). 2.Zhang,Y., Prostate Cancer Prostatic Dis. 10(3), 293-300 (2007). 3.Fletcher,G.C., Br. J. Cancer 88(4), 579-585 (2003).