Technical Data
A2298-13R
Antiplasmin, alpha2 (Alpha-2-antiplasmin, Alpha-2-AP, AAP, A2AP, Alpha-2-plasmin Inhibitor, Alpha-2-PI, API, PLI, Serpin F2, SERPINF2)
Description:
Apha-2 antiplasmin is a single-chain glycoprotein with a molecular weight of about 65000. The
normal concentration in human plasma is 60mg/ml. Platelets contain significant amounts of the
protein, which is released along with platelet factor 4, following thrombin stimulation. It can form
1:1 complexes with circulating plasmin. Alpha-2 antiplasmin is the most important inhibitor of
plasmin-mediated fibrinolysis, but also capable of inactivating factor XIIa, kallikrein, factor XIa,
thrombin and factor Xa. The importance of the alpha-2 antiplasmin as regulator of the fibrinolytic
system was detected by the discovery of a congenital deficiency.

Applications:
Suitable for use in use in ELISA, Bidimensional Electrophoresis, Immunoelectrophoresis and Double Radial Immunodiffusion (Ouchterlony). Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
1ml-20°CBlue IceHumanGoat
Concentration:
Not determined
Immunogen:
Alpha-2 antiplasmin isolated from pooled human plasma.
Purity:
Serum
Form
Supplied as a lyophilized powder, 1mg/ml sodium azide. Reconstitute with 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.
Specificity:
Recognizes human alpha-2 antiplasmin. Does not crossreact with any other human plasma proteins. A single precipitin line is obtained in bidimensional electrophoresis, immunoelectrophoresis and double radial immunodiffusion (Ouchterlony) which shows a reaction of full identity with the purified immunogen.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.