Technical Data
A2298-26C
Antithrombin-III (SERPINC1, ATIII, Serpin C1, AT3, PRO0309)
Description:
Antithrombin III is a plasma protein synthesized in the liver and has molecular weight of 58kD. Antithrombin III is a heparin-binding glycoprotein that acts as the major inhibitor of thrombin. Also it interferes with several plasma proteases, including kallikrein and factors IXa, Xa, XIa and XIIa, thereby playing a central role in regulating coagulation. It is also used as a therapeutic agent in patients with sepsis and disseminated intravascular coagulation. In addition, a number of recent studies have shown that antithrombin III has anti-inflammatory properties, which are independent of its effects on coagulation.

Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG1,kPurified
SizeStorageShippingSourceHost
50ul-20CBlue IceHumanMouse
Concentration:
Not determined
Immunogen:
Antithrombin III purified from human plasma.
Purity:
Purified
Form
Supplied as a liquid in HEPES, 0.15M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol.
Specificity:
Recognizes human SERPINC1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.