Technical Data
A2298-29G
Alpha-1-antitrypsin (Alpha-1 Protease Inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI, PRO0684, PRO2209, SERPINA1)
Description:
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (paraffin): 1:25-1:50
Optimal dilutions to be determined by the researcher.

Positive Control:
Tonsil

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
500ul-20CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Alpha-1-antitrypsin isolated from human serum. Cellular Localization: Cytoplasmic.
Purity:
Purified
Form
Supplied as a liquid, 0.05% sodium azide.
Specificity:
Recognizes human Alpha-1-antitrypsin. Species Crossreactivity: equine, mink, monkey.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Clausen et al. Acta Path Microbiol Sect A 88: 299, 1980. 2. Kalsheker et al. Alic Chim Acta 148; 157, 1985. 3. Krugliak et al. Am J Hematol 21: 99, 1982.