Plays an essential role in autophagy.
Suitable for use in ELISA and Western Blot. Other applications not tested.
Western Blot: 0.01-0.1ug/ml, observed in mouse brain lysates on ~65kD bands
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
|Synthetic peptide corresponding to C-KVEKVLSKQHSSSIN, from mouse ATG16L1, at the internal region (near the C-terminal) of the protein (NP_110430.5; NP_060444.3).|
|Purified by immunoaffinity chromatography. |
|Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.|
|Recognizes mouse ATG16L1. Species sequence homology: Canine, human and rat.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
1. Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007 May;39(5):596-604. Epub 2007 Apr 15.|