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Technical Data |
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A2298-79 |
Apicidin |
2mg |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO CAS Number: 183506-66-3 Molecular Formula: C34H49N5O6 Molecular Weight: 623.8 |
Source: Fusarium sp. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials. Kim S.H. et al. Biochem. Biophys. Res. Commun. 2004, 315, 964. 2. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Han J.W. et al. Cancer Res. 2000, 60, 6068.
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