		Technical Data
A2299-07F	APOA1, NT (Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, Apolipoprotein A-I(1-242))

Description:
Apolipoprotein A-I, is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the APOA1 gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.25mg/ml

Immunogen:

Synthetic peptide selected from the N-terminal region of human APOA1 (KLH).

Purity:

Purified by ammonium sulfate precipitation.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human APOA1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1.Simo,R., Arch. Ophthalmol. 126(8), 1076-1081 (2008). 2.Shanker,J., Lipids Health Dis 7, 33 (2008). 3.Brewer,H.B. Jr., Biochem. Biophys. Res. Commun. 80(3), 623-630 (1978).