Technical Data
A2299-68U
APOC3, NT (Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3)
Description:
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:2500 - 1:20,000
Western Blot: 1:2500-1:20,000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanGoat
Concentration:
~1mg/ml
Immunogen:
Recombinant corresponding to the N-terminus of human APOC3.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in 75mM PBS, 75mM sodium chloride, 0.02% sodium azide, pH 7.2.
Specificity:
Recognizes human APOC3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.