Technical Data
AROS (Active Regulator of SIRT1, 40S Ribosomal Protein S19-binding Protein 1, RPS19-binding Protein 1, RPS19BP1, S19BP)
AROS, a nucleolar protein with an unknown function, interacts with extraribosomal protein RPS19 playing a role in the signaling pathways that regulate rRNA transcription. The deduced aa sequence of AROS derived from cDNA defines an isoelectric point of 11.3. No known functional motifs were found in AROS except a short polylysine tract embedded in a putative nucleolar localization signal. At a basal level the protein is expressed ubiquitously with a significantly high level of expression in some tissues. The protein maps to 22q13.1 region of human chromosome.

Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
100ul-20CBlue IceHumanRabbit
Not determined.
Synthetic peptide corresponding to aa56-68 (PKSALDEYRKREC) of human AROS.
Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Recognizes human AROS. Species sequence homology: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Maeda, N. et al. Biochem. Biophys. Res. Commun. 339:41-46 (2006). 2. Johan, F. et al. Blood. 109:3152-3154 (2007).