Technical Data
A3785-20
Asialo GM1 (Asialoganglioside GM1)
Description:
A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system. It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorylation and synaptic function.

Applications:
Suitable for use in ELISA and TLC Immunoblot. Other applications have not been tested.

Recommended Dilutions:
ELISA: 1:1600 (~50ng antigen optimal detection)
TLC: 1:200
Note: Dilution in PBS, pH 7.4, is recommended.
Optimal dilutions to be determined by the researcher

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceRabbit
Concentration:
Not Determined
Immunogen:
Asialo GM1
Purity:
Serum
Form
Supplied as a liquid. No preservative added.
Specificity:
Recognizes Asialo GM-1. No crossreactivity with other carbohydrate epitopes.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Yoshino, H., et al., J. Neurochemistry, 61: 658 (1993). 2. Kusunoki, S., et al., Neurology, 37: 1,795 (1987).