Technical Data
Aspartate, Control Peptide (Aspartic Acid) (BSA)
Molecular Biology Storage: -20CShipping: Blue Ice
A distinct step in inter cellular communication involves termination of synaptic transmission via the removal of neurotransmitters by specialized transporters. The regulated exocytotoic release of neurotransmitters in response to neural activity requires storage within intracellular vesicles. In the nervous system, these vesicles are the synaptic vesicles that are derived from the endosomal compartment, whereas in endocrine cells larger secretory granules, such as the chromaffin granules of adrenal medulla, are derived from the trans golgi networks. Glutamate is the main excitatory neurotransmitter in the brain. To date five glutamate Transporters have been cloned: GLAST (EAAT1), GLT1 (EAAT2), EAAC1 (EAAT3), EAAT4, and EAAT5. These transporters are believed to be critical in reducing potentially toxic extracellular concentration of glutamate by rapid uptake into nerve terminals and glial cells.

L-Aspartic acid (BSA).

Suitable for use in ELISA and Western Blot as protein control. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source: Synthetic peptide
Purity: Purified
Concentration: Not determined.
Form: Supplied as a lyophilized powder from PBS, 0.05% sodium azide.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Tanaka, K. (1993) Neurosci. Lett. 16:149. 2. Shashidharan, P. et al (1993) BBA 1216:161. 3. Rothstein, J. D. et al (1994) Neuron 13:713. 4. Rothstein, J. D. et al (1995) Ann Neurol 38:

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.