Technical Data
A3884
Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)
1mg
Biochemicals Storage: +4CShipping: Blue Ice
A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells.

Purity: >99% by HPLC

Solubility: Soluble in ethanol, methanol, DMF or DMSO.

CAS Number:
577-64-0

Molecular Formula:
C17H16O8

Molecular Weight:
348.3
Source: Aspergillus terreus

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced
tube formation of HUVECs. Lee H.J. et al. J. Antibiot. 2002, 55, 552.
2. Asterric acid, a new endothelin binding inhibitor. Ohashi H. et al. J. Antibiot. 1992, 45, 1684.
3. Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling:
isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones,
questin and questinol. Mahmoodian A. et al. Biochem. J. 1964, 92, 369.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.