Technical Data
A3884
Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)
1mg
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Technical Data |
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A3884 |
Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A) |
1mg |
| Biochemicals | Storage: +4°CShipping: Blue Ice |
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A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells. Purity: >99% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO. CAS Number: 577-64-0 Molecular Formula: C17H16O8 Molecular Weight: 348.3 |
Source: Aspergillus terreus Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs. Lee H.J. et al. J. Antibiot. 2002, 55, 552. 2. Asterric acid, a new endothelin binding inhibitor. Ohashi H. et al. J. Antibiot. 1992, 45, 1684. 3. Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, questin and questinol. Mahmoodian A. et al. Biochem. J. 1964, 92, 369.
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