Technical Data
ATP7A (Copper-transporting ATPase 1, Copper Pump 1, Menkes Disease-associated Protein, MC1, MNK)
May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:8000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabAffinity Purified
100ug-20CBlue IceHumanGoat
Synthetic peptide corresponding to C-HKNNWNIEDNNIKN, from ATP7A, at the internal region of the protein (NP_000043.3).
Purified by immunoaffinity chromatography.
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Recognizes ATP7A. Species sequence homology: Human.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Schlief ML, West T, Craig AM, Holtzman DM, Gitlin JD. Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14919-24. Epub 2006 Sep 26.