Technical Data
A3999-82D
ATP7B (Copper-transporting ATPase 2, Copper Pump 2, Wilson Disease-associated Protein, WND/140kD, WND, WC1, PWD)
Description:
ATP7B is a member of the P-type cation transport ATPase family and has several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. It functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Mutations in ATP7B have been associated with Wilson disease (WD) (1).

Applications:
Suitable for use in Western Blot, Immunocytochemistry and Flow cytometry. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000-1:10,000
Immunocytochemistry: 1:100-1:250
Flow cytometry: 1:10-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
TypeIsotypeCloneGrade
MabEPR6794Supernatant
SizeStorageShippingSourceHost
100ul-20°CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Synthetic peptide corresponding to residues on the C-terminus in human ATP7B.
Purity:
Supernatant
Form
Supplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
Specificity:
Recognizes human ATP7B.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.