		Technical Data
A4189-07	ARK1, 2 (Serine/Threonine-protein Kinase 6, Aurora Kinase A, AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6/Serine/Threonine-protein Kinase 12, Aurora Kinase B, AURKB, AIK2, AIM1, ARK2, STK12)

Description:
The Aurora gene, a serine-threonine kinase, orginally discovered in Drosophila, has been found to be responsible for a chromosomal segregation defect. The mammalian homologues of Drosophila Aurora have been termed ARK1 (Aurora-related kinase 1) and ARK2.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 2-4ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
HCT-116

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptides corresponding to aa2-16 and 157-170 of human ARK.

Purity:

Purified by Protein G affinity Chromatography.

Form

Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.

Specificity:

Recognizes human ARK1 and 2. Species sequence homology: mouse and rat.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Shindo,M., Nakano,H., Kuroyanagi,H., Shirasawa,T., Mihara,M., Gilbert,D.J., Jenkins,N.A., Copeland,N.G., Yagita,H. and Okumura,K. cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2. Biochem. Biophys. Res. Commun. 244 (1), 285-292 (1998).