Technical Data
B0003-64K
BAFF (B cell Activating Factor belonging to TNF Family, BLyS, TALL-1, THANK)
Description:
Applications:
Suitable for use in Flow Cytometry, Immunocytochemistry, and Western Blot. Other applications have not been tested.

Recommended Dilution:
Flow Cytometry: 1:1000
Optimal dilution to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50), aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

TypeIsotypeCloneGrade
MabIgG2a6D8Highly Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRat
Concentration:
~1mg/ml
Immunogen:
Recombinant human soluble BAFF (aa 83-285).
Purity:
Highly purified (SDS-PAGE).
Form
Supplied as a liquid in PBS containing 0.02% sodium azide.
Specificity:
Recognizes membrane-bound human BAFF. Detects endogenous protein by FC.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Product Specific Literature References
1. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth: P. Schneider, et al.; J. Exp. Med. 189, 1747 (1999)
2. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000)
3. A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth: P. Rennert, et al.; J. Exp. Med. 192, 1677 (2000)
4. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone: J. Moreaux, et al.; Blood 103, 3148 (2004)

GENERAL LITERATURE REFERENCES
1. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth: P. Schneider, et al.; J. Exp. Med. 189, 1747 (1999)
2. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000)