Technical Data
B0003-70A
Bafilomycin A1
1mg
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Technical Data |
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B0003-70A |
Bafilomycin A1 |
1mg |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. Related to: Bafilomycin B1, Bafilomycin C1, Concanamycin A Solubility: Freely soluble in DMSO; may react with methanol or ethanol, so these solvents are not recommended for stock solutions; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Melting Point: 151.5-152ºC Elemental Analysis: Calculated: C: 67.49% H: 9.39% Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Protect from light. CAS Number: 88899-55-2 Molecular Formula: C35H58O9 Molecular Weight: 622.8 |
Source: Streptomyces sp. MST-AS5338 Purity: ~90% by HPLC Form: Supplied as a white solid. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Bowman, E.J., et al., Proc. Natl Acad. Sci. USA 85: 7972 (1988). 2. Yoshimori, T., et al., J. Biol. Chem. 266: 17,707 (1991). 3. Niikura, K., Drug News Perspect. 19: 139 (2006).
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