Technical Data
B0395
BCA-1 Human, Recombinant (B Cell Attracting Chemokine1, B Lymphocyte Chemoattractant, BLC, CXCL13, BLR1 Ligand)
5ug
20ug
20ug
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Technical Data |
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B0395 |
BCA-1 Human, Recombinant (B Cell Attracting Chemokine1, B Lymphocyte Chemoattractant, BLC, CXCL13, BLR1 Ligand) |
5ug 20ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3kD protein containing 85 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines. AA Sequence: VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP Biological Activity: Determined by its ability to chemoattract human B cells using a concentration range of 1-10ng/ml. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with Acetic acid. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 10.3kD |
Source: E. coli Purity: 98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug) Form: Supplied as a lyophilized powder with no additives. Reconstitute with Acetic acid to a concentration of 0.1-1.0mg/ml. Do not vortex. Further dilute with PBS, 0.1% BSA or HSA. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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