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Technical Data |
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B0410 |
B Cell Maturation Protein (BCMA), Recombinant, Human |
5ug 20ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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BCMA is a member of the TNF receptor superfamily. It binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines. It plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184aa type I transmembrane protein, which contains a 54aa extracellular domain, a 23aa transmembrane domain, and a 107aa extracellular domain. Recombinant soluble BCMA is a 50aa polypeptide (5.3kD) comprising the TNFR homologous region of the BCMA protein. Recombinant protein corresponding to human B Cell Maturation Protein expressed in E. coli AA Sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O, 0.1% BSA or HSA. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Country of Origin: USA Molecular Weight: 5.3kD |
Source: Human, recombinant expressed in E. coli Purity: 95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug) Form: Supplied as a lyophilized powder without additives. Reconstitute in sterile ddH2O, 0.1% BSA or HSA to 0.1-1mg/ml. Do not vortex. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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