Technical Data
B0807-11J1
BCL6 (B-cell Lymphoma 6 Protein, BCL-6, Zinc Finger Protein 51, LAZ-3 Protein, B-cell Lymphoma 5 Protein, BCL-5, Zinc Finger And BTB Domain-containing Protein 27, ZNF51, ZBTB27, LAZ3, BCL5)
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Technical Data |
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B0807-11J1 |
BCL6 (B-cell Lymphoma 6 Protein, BCL-6, Zinc Finger Protein 51, LAZ-3 Protein, B-cell Lymphoma 5 Protein, BCL-5, Zinc Finger And BTB Domain-containing Protein 27, ZNF51, ZBTB27, LAZ3, BCL5) |
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Description: Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2.5-5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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