Technical Data
B0901
BD2, Recombinant, Human (beta Defensin-2)
5ug
20ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
Recombinant Human beta-defensin-2
(BD-2) is an antimicrobial peptide which belongs to the distinct family of beta-defensins. Recent studies have shown that the beta-defensins are present in the human airways. It may be relevant to the pathogenesis of cystic fibrosis lung disease. Recombinant Human BD-2 is a 4.3kD protein containing 41 amino acid residues.

Rrecombinant protein corresponding to human BD2, expressed in E. coli

Biological Activity:
Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10-100ng/ml.

Amino Acid Sequence:
GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKKP

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with 10mM acetic acid. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Country of Origin:
USA

Molecular Weight:
4.3kD
Source: E. coli
Purity: 98% by SDS-PAGE and HPLC Endotoxin: 0.1ng/ug (1EU/ug)
Form: Supplied as a lyophilized powder. Reconstitute in 10mM acetic acid to a concentration of 0.1-1mg/ml. Do not vortex. THIS SOLUTION CAN THEN BE DILUTED INTO OTHER AQUEOUS SOLUTIONS.


Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Harder, J., J. Bio. Chem.,2002, 277: 46779-46784. 2. Starner,TD., Infection and Immunity, 2002, 70: 5287-5289. 3. Schibli, DJ., J. Bio. Chem., 2002, 277: 8279-8289. 4. Hoover DM., J. Biol. Chem., 2002, 275:.32911-32918.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.