Technical Data
BD4 (beta Defensin-4) (Biotin)
Defensin beta 4 (BD4), a secreted cationic antimicrobial peptide and member of the beta-defensin family, highly expressed in the testis, which plays an important role in innate immunity. Studies have shown that the expression of BD-4 is up-regulated in respiratory epithelial cells, following infection by both gram-positive and gram-negative bacteria, and that BD-4 acts in synergy with lysozyme and BD-3.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 0.25-1ug/ml
Western Blot: 0.1- 0.2ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgGAffinity Purified
50ug-20CBlue IceHumanRabbit
Recombinant human defensin beta 4.
Purified by immunoaffinity chromatography.
Supplied as a lyophilized powder in PBS, pH7.2. Labeled with Biotin. Reconstitute with 500ul sterile PBS, 0.1% BSA.
Recognizes human defensin beta 4 (BD4).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Conejo-Garcia, al. (2001) Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity FASEB. J. 15:1819-1821.