Technical Data
BD4, Recombinant, Human (beta Defensin-4)
Molecular Biology Storage: -20CShipping: Blue Ice
Defensin beta 4 (BD-4) is a secreted cationic antimicrobial peptide and member of the beta-defensin family, highly expressed in the testis, which plays an important role in innate immunity. Studies have shown that the expression of BD-4 is up-regulated in respiratory epithelial cells, following infection by both gram-positive and gram-negative bacteria, and that BD-4 acts in synergy with lysozyme and BD-3.


Suitable for use in Functional Assays. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Endotoxin: 1EU/ug

Molecular Weight: 6.0kD (50 amino acid residues)

Biological Activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100ng/ml.

Storage and Stability:
Lyophilized powder may be stored at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source: E. coli
Purity: 98% (SDS PAGE and HPLC).
Concentration: ~0.1mg/ml
Form: Supplied as a lyophilized powder. Reconstitute with 200ul dH20.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.