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Technical Data |
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B1075-04 |
Benzodiazepine |
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Description: The term benzodiazepine refers to the portion of the structure composed of a benzene ring fused to a seven membered diazepine ring. Benzodiazepine is a central nervous system depressants, a sedative hypnotic agent. Benzodiazepine receptors are located on the alpha subunit of the GABA receptor located almost exclusively on postsynaptic nerve endings in the CNS (especially cerebral cortex). Benzodiazepines enhance the GABA transmitter in the opening of postsynaptic chloride channels which leads to hyperpolarization of cell membranes. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: ELISA: 1:4000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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