Technical Data
B1081-40A
Betacellulin, Recombinant, Human
5ug
20ug
20ug
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Technical Data |
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B1081-40A |
Betacellulin, Recombinant, Human |
5ug 20ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0kD transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0kD monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is 0.05ng/ml. Specific activity: 2x10e7units/mg. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile ddH2O, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.Country of Origin: USA Molecular Weight: 9.0kD |
Source: E. coli Purity: 98% by SDS-PAGE and HPLC analyses. Endoxoxin: 0.1EU/ug Form: Supplied as lyophilized powder. Reconstitute in sterile ddH2O, to 0.1-1mg/ml, which can then be further diluted to other aqueous solutions Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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