Technical Data
B1081-40H
Betacellulin Recombinant, Human (BTC)
20ug
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Technical Data |
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B1081-40H |
Betacellulin Recombinant, Human (BTC) |
20ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Betacellulin (BTC) is a widely expressed EGF-related polypeptide growth factor, proteolytically processed into a soluble mature form, which acts as a potent inducer of mitosis in vascular smooth muscle cells and retinal pigment epithelial cells. BTC signals through binding to the homodimeric ErbB-1 and ErbB-4 receptors, but also appears to uniquely bind to and activate all known heterodimeric ErbB receptors. Source: Recombinant Betacellulin expressed in E.coli. Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is 0.05ng/ml, corresponding to a specific activity of 2x10e7units/mg. Applications: Suitable for use in Functional Assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 9.0kD |
Source: E.coli. Purity: ~98% by SDS PAGE and HPLC analysis. Endotoxin: 1EU/ug. Form: Supplied as a lyophilized powder. Reconstitute with 200ul sterile dH2O . Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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