		Technical Data
B1081-40M	BTC, Recombinant, Human, aa32-111, His-tag (Probetacellulin, Betacellulin)	50ug 250ug

Growth Factors, Cytokines

Storage: -20°CShipping: Blue Ice

BTC (Betacellulin) is a member of the EGF family of growth factors and contains 1 EGF-like domain. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. The effects of BTC are probably mediated by the EGF receptor and other related receptors.

Source:
Recombinant corresponding to aa32-111 from human BTC, fused to His-tag at N-terminal expressed in E.coli.

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MDGNSTRSPE TNGLLCGDPE ENCAATTTQS KRKGHFSRCP KQYKHYCIKG RCRFVVAEQT PSCVCDEGYI GARCERVDLF Y

Molecular Weight:
~11.3kD (MALDI-TOF)

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
~11.3kD

Source: E.coli
Purity: ~90% (SDS-PAGE)
Concentration: ~0.1mg/ml
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 5mM DTT, 20% glycerol, 200mM sodium chloride.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

1. Gratao AA, et al. (2008) Biol Reprod. 78(1):43-52. 2. Genetos DC, et al. (2010) Cell Tissue Res. 340(1):81-9.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.