Technical Data
B1200-01N
Bin1 (Myc Box-dependent-interacting Protein 1, Amphiphysin II, Amphiphysin-like Protein, Bin1 Protein, Myc Box-dependent-interacting Protein 1, Bridging Integrator 1, SH3 Domain-containing Protein 9, Amphl, Sh3p9)
Description:
BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly through activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouseRabbit
Concentration:
~0.1mg/ml
Immunogen:
Synthetic peptide corresponding to aa578 from mouse BIN-1.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.1% BSA, 0.01% thimerosal, 30% glycerol.
Specificity:
Recognizes mouse BIN-1 at ~45kD and ~65kD. Species Crossreactivity: human and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.