Technical Data
B2125-13
Blood Group B
Description:
The ABO system is based on differential gylcosylation of lipid or protein on blood cells. The basic carbohydrate chain extending from the protein or lipid is, eg, Type O: Protein or Lipid - Glucose--N-Acetylglucosamine--Galactose--Fucose. The galactose residue can have an additional sugar residue (in addition to the Fucose) attached to it. If the additional residue is N-Acetylgalactosamine, then the individual is Type A. If the additional residue is Galactose, then the individual is Type B. Type A's and Type B's actually differ because they have different enzymes for glycosylation at the Galactose site. Type A: N-Acetylgalactosamine glycosylation; Type B: Galactose glycosylation. Type AB: individuals with both enzymes. (Type AB individuals have N-Acetylgalactosamine on some galactose sites and Galactose on other galactose sites. Type AB are a mixture of Type A and Type B blood.) Type O individuals do not have the enzymes for glycosylation on the galactose site.

Applications:
Suitable for use in blood group typing in direct agglutination tests (slide, tube and microplate). Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgM1V016Affinity Purified
SizeStorageShippingSourceHost
100ug4C Do Not FreezeBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Blood Group B
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in 0.3M sodium chloride, 1.25mM EDTA, 0.1% sodium azide.
Specificity:
Recognizes B human blood antigen. Weak crossreactity with A1, must be diluted appropriately for automated tests.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.