Technical Data
B2553-11E
Bone Morphogenetic Protein 3b, Recombinant, Human (BMP3b, Growth Differentiation Factor 10, GDF10)
100ug
Growth Factors, Cytokines Storage: -20C/-70CShipping: Dry Ice
GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.

Source:
Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight:
12.5kD(111aa)

AA Sequence:
MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R

Storage and Stability:
For long-term storage, aliquot and store at -20C/-70C. Aliquots are stable for at least 6 months at -20C/-70C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.


Source: E. coli
Purity: ~95% by SDS-PAGE.
Concentration: As reported
Form: Supplied as a liquid in 10mM sodium citrate, pH 3.5, 10% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Cunningham NS., et al. (1995) Growth Factors. 12(2):99-109. Ducy P., et al. (2000) Kidney Int. 57(6):2207-14.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.