		Technical Data
B2700-01E	Brain-Derived Neurotrophic Factor, Recombinant, Human (BDNF)	25ug

Growth Factors, Cytokines

Storage: -20°CShipping: Blue Ice

Human BDNF is a member of the NGF family of neurotrophic growth factors which supports neuron proliferation and survival. BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface seceptor called gp145/trkB.

Biological Activity:
Determined by its ability to stimulate chick E8 neurite outgrowth. The ED50 is 0.1-0.01ng/ml.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 1 month at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
~27kD

Source: E. coli
Purity: ~95% as determined by SDS-PAGE and HPLC Endotoxin: 1EU/ug (LAL)
Form: Supplied as a lyophilized powder from 10mM acetic acid, 0.3M sodium chloride. Reconstitute with sterile dH2O to 0.1mg/ml.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.