		Technical Data
B2700-02Q	BDNF, NT (Brain-derived Neurotrophic Factor, Abrineurin)

Description:
BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1000
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.25mg/ml

Immunogen:

Synthetic peptide selected from within aa14-44 of the N-terminal region of human BDNF (KLH).

Purity:

Purified by ammonium sulfate precipitation.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human BDNF.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Jiang, H., Clin. Chim. Acta 400(1-2): 3-7 (2009). 2. Liu, L., Psychiatr. Genet. 18(6): 267-274 (2008). 3. Dmitrzak-Weglarz, M., Pharmacogenomics 9(11): 1595-1603 (2008).