Technical Data
B2702-34A
Brain Natriuretic Peptide, aa1-21 (BNP)
Description:
Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation.

BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at 4C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a21-6-6Affinity Purified
SizeStorageShippingSourceHost
10ug-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Synthetic human pro-BNP (aa 1-21) polylysine conjugated (HPLGSPGSASDLETSGLQEQR)
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a lyophilized powder in 200mM Na Citrate-Tris, 500mM sodium chloride, pH 7.5, 0.02% sodium azide.
Specificity:
Recognizes synthetic human pro-Brain Natriuretic Peptide (aa 1-21)
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.