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Technical Data |
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C0006-02K |
CCL14, aa20-93, Recombinant, Human (Chemokine (C-C Motif) Ligand 14, C-C Motif Chemokine 14, CC-1, CC-3, CKB1, Chemokine CC-1/CC-3, FLJ16015, HCC-1/HCC-3, HCC-1, HCC-1(1-74), HCC-3, MCIF, NCC2, NCC2, NCC-2, SCYL2, Small-inducible Cytokine A14, SCYA14, SY1 |
100ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1 . It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1(9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5. Source: Recombinant corresponding to human CCL14, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~10.9kD Sequences of Amino Acids: MGSSHHHHHH SSGLVPRGSH MTKTESSSRG PYHPSECCFT YTTYKIPRQR IMDYYETNSQ CSKPGIVFIT KRGHSVCTNP SDKWVQDYIK DMKEN Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: ~10.9kD |
Source: E. coli Purity: ~95% (SDS-PAGE) Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Munch J., et al. (2002) Antimicrob Agents Chemother. 46:982-990. 2. Blain K.Y., et al. (2007) Biochemistry. 46:10008-10015.
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