Technical Data
C0009-95
Complement Activation Blocker-2 (CAB-2)
Description:
CAB-2 is a soluble chimeric protein derived from human decay accelerating factor (CD55) and membrane cofactor protein (CD46). It inhibits C3 and C5 convertases of both classical and alternative pathway. It also blocks the activation of complement in vivo.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:2000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG19F596Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
Human complement activation protein blocker-2, CAB-2 (110kD)
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2.
Specificity:
Recognizes human CAB-2
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Higgins, P.J. et. al. (1997) J. Immunol. 158,2872 - 2881