Technical Data
C0010-02G
Complement C1q (Complement Component 1, q Subcomponent) (HRP)
Description:
Human C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilutions:
ELISA: 1:100-1:400
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4░C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20░C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.áLabeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
1ml-20░CBlue IceHumanSheep
Concentration:
~1mg/ml
Immunogen:
Human C1q
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, 0.01% thimerosal, HRP stabilizer. Labeled with horseradish peroxidase (HRP).
Specificity:
Recognizes human C1q. May react with C1q from other species.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Nascimento, E.J. et al. (2009) Alternative complement pathway deregulation is correlated with dengue severity. PLoS One. 4:e6782. 2. Lewis, M.J. et al. (2007) The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies. Mol Immunol. 45: 818-27.