Technical Data
C0010-10L
C1QA, CT (Complement C1q Subcomponent Subunit A)
Description:
C1QA is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on hromosome 1.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the C-terminal region of human C1QA (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human C1QA.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Dardiotis,E., Koutsou,P. J. Neurol. Sci. (2009) In press. 2.Martens,H.A., Zuurman,M.W. Ann. Rheum. Dis. 68(5), 715-720 (2009). 3.Racila,E., Link,B.K. Clin. Cancer Res. 14(20), 6697-6703 (2008). 4.Sjoberg,A.P., Nystrom,S. Mol. Immunol. 45(11), 3213-3221 (2008).