Technical Data
Cbl-b (CBLb, Cas-Br-M (murine) Ecotropic Retroviral Transforming Sequence b, Casitas B-lineage Lymphoma Proto-oncogene b, Nbla00127, RING Finger Protein 56, RNF56)
CBLB (Cas Br M (murine) ecotropic retroviral transforming sequence b) has high homology to CBL, the proto-oncogene that induces pre-B cell lymphomas and myeloid leukemias in mice. Like CBL, CBLB contains putative nuclear localization signal, zinc finger, leucine zipper, and proline-rich domains. CBLB associates with FYN, FGR, and PLCG1.

Suitable for use in Dot Blot and Western Blot. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 0.2-2ug/ml
Optimal dilutions to be determined by researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
MabIgG2a8C51Affinity Purified
50ug-20CBlue IceHumanMouse
Partial recombinant protein corresponding to the C-terminal region of human Cbl-b.
Purified by Protein G affinity chromatography.
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Recognizes human Cbl-b at ~109kD in HeLa cell lysate. Species Crossreactivity: mouse (NIH3T3 cells).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.