Technical Data
C0045-75D
C4.4A (LYPD3, Y6/PLAUR domain containing 3 GPI-anchored metastasis-associated protein C4.4A homolog, Ly6/PLAUR domain-containing protein 3 precursor, Matrigel-induced gene C4 protein, MIG-C4, UNQ491/PRO1007)
Description:
C4.4A is a structural homolog of the urokinase-type plasminogen activator receptor (uPAR). It was originally identified as a metastasis-associated membrane protein in malignant urothelium. In literature IHC studies, staining has been observed in suprabasal keratinocytes of chronic wounds and the amniotic membrane of placenta. ISH analysis demonstrated expression in urothelium of the ureter. C4.4A expression has also been found to be upregulated in breast tumors when compare to normal breast tissue.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 10-12.5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to 14aa from the N-terminal domain of human LYPD3.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.1% sodium azide.
Specificity:
Recognizes human LYPD3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.