		Technical Data
C0050-20B	CA15-3 Human Cancer Associated Antigen (Tumor Cells)

Description:
The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20aa tandem repeat (VNTR polymorphism).

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
ELISA (Capture or detection): Forms a suitable pair with C0050-20A.
Immunohistochemistry: Frozen or paraffin sections
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgG1,k	9j113	Affinity Purified

Size		Storage	Shipping	Source	Host
1mg		-20°C	Blue Ice	Human	Mouse

Concentration:

~1mg/ml

Immunogen:

Purity:

Purified by Protein A/G affinity chromatography.

Form

Supplied as a liquid in PBS, pH 7.4.

Specificity:

Recognizes the hexapeptide (TRPAPG) of the human CA15-3 Human Cancer Associated Antigen (Tumor Cells). Specific for the tandem repeat of the MUC-1 core.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.