Technical Data
C0104-70A
CACNA2D1, NT (Voltage-dependent Calcium Channel Subunit alpha-2/delta-1, Voltage-gated Calcium Channel Subunit alpha-2/delta-1, Voltage-dependent Calcium Channel Subunit alpha-2-1, Voltage-dependent Calcium Channel Subunit delta-1, MHS3, CCHL2A, CACNL2A)
Description:
CACNA2D1 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
~0.25mg/ml
Immunogen:
Synthetic peptide selected from the N-terminal region of human CACNA2D1 (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human CACNA2D1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Williams,M.E., et.al., Neuron 8(1), 71-84 (1992). 2. Chaudhuri,D., et.al., J. Gen. Physiol. 129(5), 385-401 (2007).