Technical Data
C0104-70B
CACNA2D1 (Voltage-dependent Calcium Channel Subunit alpha-2/delta-1, Voltage-gated Calcium Channel Subunit alpha-2/delta-1, CACNL2A, CCHL2A, MHS3)
Description:
CACNA2D1 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.03-0.1ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Human Brain (Cerebellum) lysate

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to [BLAST]C-QEIFNKYNKDKKVR[BLAST], from the internal region of the protein sequence according to NP_000713.2.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes human CACNA2D1. Species sequence homology: canine, mouse, rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.