Description:
Applications:
Western Blotting: 1:500-1:1000
Optimal working dilutions to be determined by researcher.
|
| Type | Isotype | Clone | Grade |
|---|
| Pab | IgG | | Affinity Purified |
|
| Size | | Storage | Shipping | Source | Host |
|---|
| 100ug | | -20°C | Blue Ice | Mouse | Rabbit |
|
| Concentration: |
| ~0.5mg/ml |
| Immunogen: |
| Synthetic peptide corresponding to amino acids 205-222 of mouse CAD. |
| Purity: |
| Purified IgG prepared by affinity chromatography. |
| Form |
| Supplied as a liquid in PBS with 0.02% sodium azide. |
| Specificity: |
| CAD (Caspase Activated Deoxyribonuclease) is the mouse homologue of human DFF-40.CAD is released and activated by caspase cleavage of ICAD and eventually causes degradation of nuclear DNA. Recognizes the 40kD CAD in Western blots. |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
1. Enari, M. et al. (1998). A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391: 43-50.2. Sakahira, H. et al. (1998). Cleavage of CAD inhibitor in CAD activation and DNA degradati
|
|
