Technical Data
C0114-01
Calcineurin, NT (Serine/Threonine Protein Phosphatase 2B Catalytic Subunit, alpha Isoform, Calmodulin-dependent Calcineurin A Subunit, alpha Isoform, CAM-PRP Catalytic Subunit, PPP3CA, CALNA, CNA)
Description:
PPP3CA is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. PPP3CA dephosphorylates HSPB1 and SSH1.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the N-terminal region of human PPP3CA (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human PPP3CA.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Rodriguez, A., et al., J. Biol. Chem. 280(11):9980-9984 (2005). 2.Shirane, M., et al., Nat. Cell Biol. 5(1):28-37 (2003). 3.Bengoechea-Alonso, M.T., et al., Nitric Oxide 8(1):65-74 (2003). 4.Huai, Q., et al., Proc. Natl. Acad. Sci. USA 99(19):12037-12042 (2002). 5.Bennasser, Y., et al., Virology 303(1):174-180 (2002).