Technical Data
Calcitonin is a 32aa peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

Suitable for use in Immunohistochemistry. Other aplications not tested.

Recommended Dilutions:
Immunohistochemistry (Formalin/paraffin): 1:200 for 30 minutes at RT. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues. Optimal dilutions to be determined by the researcher.

Recommended Positive Control:
Thyroid or medullary carcinoma

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
500ul-20CBlue IceHumanRabbit
Not Determined
Synthetic peptide corresponding to aa1-32 of human calcitonin. Cellular Localization: Cytoplasmic.
Supplied as a liquid, 15mM sodium azide.
Recognizes human Calcitonin. Species Crossreactivity: monkey, mouse, rat, canine, equine, sheep and porcine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
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