Technical Data
Calcitonin (Alpha CGRP, CALC1, CALCA, Calcitonin related polypeptide alpha, CGRP1, CGRP, CT, Katacalcin, KC, MGC126648)
Immunohistochemical staining with calcitonin antibody has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies of calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities.

Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Paraffin, frozen): 1:200-1:1000
Optimal dilutions to be determined by the researcher.

Positive Control:
Medullary Carcinoma of Thyroid

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabAffinity Purified
500ul-20CBlue IceHumanRabbit
Not determined.
Purified by immunoaffinity chromatography.
Supplied as a liquid in PBS, pH7.4, protein base, sodium azide.
Recognizes Calcitonin. Staining pattern: Cytoplasmic.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Copp, DH, et al., Endocrinology 1962; 70:638-649, 2. Kameda, Y et al., Cell Tissue Res 1980; 206:403-415, 3. Coombes, RC et al., Lancet 1974; 1:1080-1083, 4. Dayal Y, et al., Cancer 1979; 43:1331-1338, 5. DeLellis, RA et al., Am J Clin Pathol 1978; 7(4):587-29.