Technical Data
C0115-08H
Calcitonin (Alpha CGRP, CALC1, CALCA, Calcitonin related polypeptide alpha, CGRP1, CGRP, CT, Katacalcin, KC, MGC126648)
Description:
Immunohistochemical staining with calcitonin antibody has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies of calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Paraffin, frozen): 1:200-1:1000
Optimal dilutions to be determined by the researcher.

Positive Control:
Medullary Carcinoma of Thyroid

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
500ul-20CBlue IceHumanRabbit
Concentration:
Not determined.
Immunogen:
Calcitonin.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, pH7.4, protein base, sodium azide.
Specificity:
Recognizes Calcitonin. Staining pattern: Cytoplasmic.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Copp, DH, et al., Endocrinology 1962; 70:638-649, 2. Kameda, Y et al., Cell Tissue Res 1980; 206:403-415, 3. Coombes, RC et al., Lancet 1974; 1:1080-1083, 4. Dayal Y, et al., Cancer 1979; 43:1331-1338, 5. DeLellis, RA et al., Am J Clin Pathol 1978; 7(4):587-29.