		Technical Data
C0132-14G	Caldesmon (CDM, Caldesmon 1, Caldesmon-1, CALD1, H CAD, H-CAD, L-CAD, MGC21352, NAG22)

Description:
Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Two closely related variants of human caldesmon have been identified which differ in their eletrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kD) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kD) is found in nonmuscle tissue and cells. Neither of the two variants has been detected in skeletal muscle.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgG1	10B424	Affinity Purified

Size		Storage	Shipping	Source	Host
200ug		-20°C	Blue Ice	Duck	Mouse

Concentration:

~1mg/ml

Immunogen:

Duck gizzard caldesmon (heavy type).

Purity:

Purified by Protein A affinity chromatography.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes duck CALDESMON. Reacts with the high molecular weight (120-150kD) and a low molecular weight (71-80kD) forms of caldesmon. Species Crossreactivity: chicken, human.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.