		Technical Data
C1035-22A	CAMK1, CT (Calcium/Calmodulin-dependent Protein Kinase Type 1, CaM Kinase I, CaM-KI, CaM Kinase I alpha, CaMKI-alpha)

Description:
Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

Immunogen:

Synthetic peptide selected from the C-terminal region of human CAMK1 (KLH).

Purity:

Purified by Protein G affinity chromatography.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human CAMK1. Species Crossreactivity: mouse, rat, primate.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1.Condon, J.C., et al., Endocrinology 143(9):3651-3657 (2002). 2.Chin, D., et al., J. Biol. Chem. 272(50):31235-31240 (1997). 3.Haribabu, B., et al., EMBO J. 14(15):3679-3686 (1995). 4.Ishikawa, Y., et al., FEBS Lett. 550(1-3), 57-63 (2003).