Technical Data
C1035-25W1
CAMK2D, CT (Calcium/Calmodulin-dependent Protein Kinase Type II Subunit delta, CaM-kinase II Subunit delta, CaMK-II Subunit delta, CAMKD)
Description:
CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the C-terminal region of human CAMK2 delta (KLH).
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human CAMK2 delta. Species Crossreactivity: primate.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Rochlitz, H., et al., Diabetologia 43(4):465-473 (2000). 2.Hoch, B., et al., Circ. Res. 84(6):713-721 (1999). 3.Tombes, R.M., et al., Biochim. Biophys. Acta 1355(3):281-292 (1997).